Nanosuspention Formulation

Nanosuspention formulation can be used to improve the solubility of the poorly soluble drugs. One of the major problems associated with poorly soluble drugs is very low bioavailability. The Preparation of Nanosuspention is simple and applicable to all drugs which are water insoluble. It consists of the pure poorly water-soluble drug without any matrix material suspended in dispersion . Various techniques are used for the enhancement of the solubility of poorly soluble drugs which include physical and chemical modifications of drug and other methods like particle size reduction, crystal engineering, salt formation, solid dispersion, use of surfactant, complexation A range of parameters like solubility, stability at room temperature, compatibility with solvent, excipient, and photostability play a critical role in the successful formulation of drugs. Use of some drug which is potentially restricted because of its toxic side-effects and its poor solubility, making it unsuitable for intravenous use in patients with drug malabsorption.

  • Pharmacokinetic evaluation Nanosuspention formulations
  • Cyclosporine A-Nanosuspention
  • Preparation , optimization and in vitro characterization Nanosuspention cyclosporine
  • Pharmaceutical product development
  • Improved delivery of poorly soluble compounds using Nanoparticle technology
  • Crystalline properties of NPs

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