Nano Toxicology

Zinc oxide nanoparticles are utilized  in numerous applications, contain sunscreens, cosmetics, textiles, and electrical devices. Increased consumer and occupational exposure to potentially poses a risk for toxicity. While many studies have examined the toxicity of  little is understood  regarding the toxicological impact of inherent defects arising from batch-to-batch variations. It was hypothesized that the presence of varying chemical defects  will contribute to cellular toxicity in rat aortic endothelial cells (RAECs). Pristine and defected  (oxidized, reduced, and annealed) were prepared and assessed three major cellular outcomes; cytotoxicity/apoptosis, reactive oxygen species production and oxidative stress, and endoplasmic reticulum (ER) stress

 

  • Functional Nanomaterials
  • Molecular Engineering
  • Nanofabrication
  • Scanning Probe Techniques

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